Ionis Pharmaceuticals, Inc. (IONS) is listed on NASDAQ in Pharmaceutical Stocks. It is $61.02, -2.26%, with a $10.1B market cap. RSI is 60.3, near overbought. The latest reported quarter beat estimates. Insiders were net sellers across the listed trades.
Technical Analysis
RSI (14) 60.3 Near Overbought
Market Cap $10.1B
Volume 1.6M
Fundamentals — 10-Q Q2 2026
Revenue $514.0M
Net Income $-207.2M
EPS $-1.25
Gross Margin 98.9%
Operating Margin -42.7%
Net Margin -40.3%
P/E Ratio -48.8x
Earnings
Recent Insider Trades
| Name | Title | Type | Shares | Price | Value | Date |
|---|---|---|---|---|---|---|
| Hayden Michael R | Director | Buy | 20,000 | $52.94 | $1.1M | 2026 Jul 31 |
| Bennett C Frank | EVP, Chief Scientific Officer | Sell | 20,536 | $84.95 | $1.7M | 2026 Jul 7 |
| Diaz Allene M. | Director | Sell | 10,111 | $85.42 | $863,637 | 2026 Jul 7 |
| Kordasiewicz Holly B. | EVP, Chief Development Officer | Sell | 362 | $84.30 | $30,517 | 2026 Jul 7 |
| Klein Joseph III | Director | Sell | 11,518 | $79.04 | $910,416 | 2026 Jul 1 |
| Baroldi Joseph | EVP, Chief Business Officer | Sell | 5,635 | $80.16 | $451,699 | 2026 Jun 26 |
| O'neil Patrick R. | EVP CLO & General Counsel | Sell | 3,069 | $80.00 | $245,520 | 2026 Jun 26 |
| Schneider Eugene | EVP, Chf Clinical Develop Ofcr | Sell | 26,000 | $81.05 | $2.1M | 2026 Jun 26 |
| Monia Brett P | Chief Executive Officer | Sell | 85,637 | $79.70 | $6.8M | 2026 Jun 26 |
| Swayze Eric | EVP Research | Sell | 10,602 | $79.18 | $839,492 | 2026 Jun 25 |
| Berthelsen Spencer R | Director | Sell | 8,000 | $73.49 | $587,920 | 2026 Jun 15 |
| Kordasiewicz Holly B. | EVP, Chief Development Officer | Sell | 60,846 | $73.41 | $4.5M | 2026 Jun 12 |
| Berthelsen Spencer R | Director | Sell | 8,000 | $75.67 | $605,360 | 2026 Jun 1 |
| Monia Brett P | Chief Executive Officer | Sell | 4,536 | $78.49 | $356,012 | 2026 May 14 |
| Loscalzo Joseph | Director | Sell | 77,289 | $75.06 | $5.8M | 2026 May 4 |
| Klein Joseph III | Director | Sell | 10,111 | $73.51 | $743,238 | 2026 May 1 |
| Baroldi Joseph | EVP, Chief Business Officer | Sell | 1,626 | $71.79 | $116,727 | 2026 Apr 28 |
| Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | Sell | 4,902 | $75.17 | $368,488 | 2026 Apr 16 |
| Birchler Brian | EVP, Corp and Development Ops | Sell | 973 | $75.04 | $73,016 | 2026 Apr 16 |
| Baroldi Joseph | EVP, Chief Business Officer | Sell | 5,619 | $74.56 | $418,953 | 2026 Apr 16 |
Other Pharmaceutical Stocks
| Ticker | Price | RSI | Mkt Cap |
|---|---|---|---|
| | $1,173.34 | 46.3 | $1.1T |
| | $268.01 | 58.6 | $645.9B |
| | $148.31 | 64.1 | $365.9B |
| | $24.11 | 48.8 | $12.0B |
| | $47.41 | 37.2 | $8.0B |
| | $34.17 | 49.9 | $2.5B |
| | $44.82 | 51.9 | -- |
| | $84.85 | 71.8 | $9.0B |
Take IONS further
- Browse Pharmaceutical Stocks for the rest of the group, with what the businesses in it have in common and where they differ.
- Put IONS in a portfolio and see what it does to total return, drawdown, and how the rest of your holdings move with it. Compares against the S&P 500 over the same days, free and without an account.
- Screen for others like it by RSI, valuation, market cap, and insider activity.
- Check the earnings calendar for when Ionis Pharmaceuticals, Inc. next reports.
Set alerts on IONS
Get notified when Ionis Pharmaceuticals, Inc. hits your price targets or technical conditions are met.
Get Started Free