71 companies, largest first.
Ticker Mkt Cap
LLY
Eli Lilly and Company
$1.10T
JNJ
Johnson & Johnson
$645.88B
ONC
BeOne Medicines Ltd. - American Depositary Shares
$542.12B
ABBV
AbbVie Inc.
$451.55B
MRK
Merck & Company, Inc. Common Stock (new)
$365.91B
ABT
Abbott Laboratories
$195.84B
PFE
Pfizer, Inc.
$159.33B
VRTX
Vertex Pharmaceuticals Incorporated
$137.30B
BMY
Bristol-Myers Squibb Company
$136.00B
REGN
Regeneron Pharmaceuticals, Inc.
$82.11B
TEVA
Teva Pharmaceutical Industries Limited American Depositary Shares
$42.46B
ZTS
Zoetis Inc. Class A
$31.94B
ALNY
Alnylam Pharmaceuticals, Inc.
$31.71B
RPRX
Royalty Pharma plc - Class A Ordinary Shares
$26.83B
INSM
Insmed Incorporated
$25.88B
ROIV
Roivant Sciences Ltd. - Common Shares
$25.06B
UTHR
United Therapeutics Corporation
$22.11B
VTRS
Viatris Inc.
$18.77B
JAZZ
Jazz Pharmaceuticals plc - Ordinary Shares
$15.88B
BBIO
BridgeBio Pharma, Inc.
$14.98B
BMRN
BioMarin Pharmaceutical Inc.
$12.51B
MDGL
Madrigal Pharmaceuticals, Inc.
$12.34B
CORT
Corcept Therapeutics Incorporated
$12.30B
ELAN
Elanco Animal Health Incorporated
$12.05B
ARWR
Arrowhead Pharmaceuticals, Inc.
$12.00B
SMMT
Summit Therapeutics Inc.
$10.94B
AXSM
Axsome Therapeutics, Inc.
$10.42B
IONS
Ionis Pharmaceuticals, Inc.
$10.14B
CYTK
Cytokinetics, Incorporated
$10.03B
PRAX
Praxis Precision Medicines, Inc.
$9.63B
PTGX
Protagonist Therapeutics, Inc.
$9.33B
CRNX
Crinetics Pharmaceuticals, Inc.
$9.00B
TGTX
TG Therapeutics, Inc.
$8.25B
SYRE
Spyre Therapeutics, Inc.
$7.97B
ALKS
Alkermes plc - Ordinary Shares
$7.95B
MIRM
Mirum Pharmaceuticals, Inc. - common stock
$6.33B
ERAS
Erasca, Inc.
$6.31B
TVTX
Travere Therapeutics, Inc.
$6.19B
LQDA
Liquidia Corporation
$6.06B
ORKA
Oruka Therapeutics, Inc.
$6.04B
COGT
Cogent Biosciences, Inc.
$6.02B
KNSA
Kiniksa Pharmaceuticals International, plc - Class A Ordinary Shares
$5.98B
DNTH
Dianthus Therapeutics, Inc.
$5.92B
PTCT
PTC Therapeutics, Inc.
$5.85B
XENE
Xenon Pharmaceuticals Inc. - Common Shares
$5.81B
LGND
Ligand Pharmaceuticals Incorporated
$5.60B
DFTX
Definium Therapeutics, Inc. - Common Shares
$5.50B
ACAD
ACADIA Pharmaceuticals Inc.
$5.02B
DYN
Dyne Therapeutics, Inc.
$4.68B
INDV
Indivior Pharmaceuticals, Inc.
$4.11B
MANE
Veradermics, Incorporated
$4.10B
AMLX
Amylyx Pharmaceuticals, Inc.
$3.88B
VKTX
Viking Therapeutics, Inc.
$3.75B
QURE
uniQure N.V. - Ordinary Shares
$3.07B
SLS
SELLAS Life Sciences Group, Inc.
$2.66B
VERA
Vera Therapeutics, Inc. - Class A
$2.46B
BHC
Bausch Health Companies Inc.
$2.37B
SRPT
Sarepta Therapeutics, Inc.
$2.20B
AGIO
Agios Pharmaceuticals, Inc.
$1.99B
MNPR
Monopar Therapeutics Inc.
$753.4M
BIOA
BioAge Labs, Inc.
$443.6M
AZN
AstraZeneca PLC Ordinary Shares
—
GSK
GSK plc American Depositary Shares (Each representing two Ordinary Shares)
—
ABVX
Abivax SA - American Depositary Shares
—
LEGN
Legend Biotech Corporation - American Depositary Shares
—
SNY
Sanofi - American Depositary Shares
—
NVS
Novartis AG
—
GMAB
Genmab A/S - American Depositary Shares
—
ASND
Ascendis Pharma A/S - Ordinary Share
—
TAK
Takeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock)
—
NVO
Novo Nordisk A/S
—

About Pharmaceutical Stocks

Big pharma is a defensive sector with a hole in it. The dividends are reliable, the balance sheets are strong, and the cash flows are enormous, right up until a patent expires and a drug that was most of the profit gets copied for a fraction of the price.

That expiry is the only thing worth planning around, and it is on a published date. Every one of these companies is in a permanent race to replace revenue it is about to lose, either by discovering something or by buying whoever did. This is why the sector consolidates constantly and why an acquisition here is usually a confession about the pipeline.

Prices are the political risk. These are not businesses that set their own prices; insurers and government programs negotiate them, and any serious drug pricing reform lands directly on the margin. The group tends to be cheap relative to the market for exactly that reason. Clinical-stage developers filed alongside them are a different instrument entirely, with no revenue, a cash balance, and a binary trial result that can halve or double the stock in a morning.

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